Multi-layered polymeric nanoparticles for pH-responsive and sequenced release of theranostic agents.
نویسندگان
چکیده
In this study, multi-layered pH-responsive polymeric nanoparticles (NPs) are prepared by multiple (up to 4) emulsifications to encapsulate multiple hydrophilic and hydrophobic theranostic agents for controlled and sequenced release. It is found that the sequence of release of multiple chemotherapeutic agents from the NPs significantly affects their efficacy against cancer cells.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 36 شماره
صفحات -
تاریخ انتشار 2015